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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1A
All Species:
21.82
Human Site:
T257
Identified Species:
40
UniProt:
O95602
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95602
NP_056240.2
1720
194811
T257
I
G
K
R
G
Y
L
T
P
T
S
A
R
E
H
Chimpanzee
Pan troglodytes
XP_001135380
1723
195055
T257
I
G
K
R
G
Y
L
T
P
T
S
A
R
E
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532976
1699
192037
T239
L
G
K
R
G
Y
L
T
P
T
S
A
R
E
H
Cat
Felis silvestris
Mouse
Mus musculus
O35134
1717
194092
T264
M
G
K
R
G
Y
L
T
P
S
S
A
Q
E
H
Rat
Rattus norvegicus
O54889
1716
194174
T264
M
G
K
R
G
Y
L
T
P
S
S
A
Q
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
L76
C
E
T
C
G
K
N
L
A
D
C
L
G
H
Y
Frog
Xenopus laevis
NP_001082182
1730
195193
L262
Q
L
A
K
R
G
Y
L
T
P
N
T
T
K
E
Zebra Danio
Brachydanio rerio
XP_001922839
1693
190636
T249
L
T
K
R
I
F
L
T
P
S
V
A
R
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91875
1642
185391
C255
K
V
I
F
A
D
E
C
R
R
Y
L
R
Q
I
Honey Bee
Apis mellifera
XP_001121092
1665
190473
N241
K
L
W
Q
N
E
K
N
F
L
K
V
I
I
P
Nematode Worm
Caenorhab. elegans
NP_001022450
1737
195064
A313
D
K
L
A
W
R
G
A
E
V
R
E
H
F
R
Sea Urchin
Strong. purpuratus
XP_794863
1742
194988
A256
K
H
L
R
N
L
M
A
N
D
G
V
G
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10964
1664
186413
I315
P
K
T
G
S
T
Y
I
L
S
T
E
V
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
90
N.A.
86.8
87.9
N.A.
N.A.
27
68.1
67.9
N.A.
43.7
43.6
39.3
46.8
Protein Similarity:
100
99.1
N.A.
94.4
N.A.
93.3
93.8
N.A.
N.A.
43.9
81.7
81.3
N.A.
61.4
61.5
57.4
64.4
P-Site Identity:
100
100
N.A.
93.3
N.A.
80
80
N.A.
N.A.
6.6
0
60
N.A.
6.6
0
0
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
13.3
20
80
N.A.
13.3
6.6
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
0
16
8
0
0
47
0
0
0
% A
% Cys:
8
0
0
8
0
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
0
0
16
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
8
8
0
8
0
0
16
0
47
8
% E
% Phe:
0
0
0
8
0
8
0
0
8
0
0
0
0
8
0
% F
% Gly:
0
39
0
8
47
8
8
0
0
0
8
0
16
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
8
8
47
% H
% Ile:
16
0
8
0
8
0
0
8
0
0
0
0
8
8
8
% I
% Lys:
24
16
47
8
0
8
8
0
0
0
8
0
0
16
0
% K
% Leu:
16
16
16
0
0
8
47
16
8
8
0
16
0
8
0
% L
% Met:
16
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
16
0
8
8
8
0
8
0
0
0
8
% N
% Pro:
8
0
0
0
0
0
0
0
47
8
0
0
0
0
8
% P
% Gln:
8
0
0
8
0
0
0
0
0
0
0
0
16
8
0
% Q
% Arg:
0
0
0
54
8
8
0
0
8
8
8
0
39
0
16
% R
% Ser:
0
0
0
0
8
0
0
0
0
31
39
0
0
0
0
% S
% Thr:
0
8
16
0
0
8
0
47
8
24
8
8
8
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
8
8
16
8
0
0
% V
% Trp:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
39
16
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _